Diagnostic imaging of melanocytic skin tumors

Spindle cell melanocytic tumors

pseudoinclusions are sometimes evident and mild nuclear pleomorphism is typical. Mitoses are either absent or extremely infrequent. By definition dendritic cells are said not to be seen in this lesion. The growth pattern often presents a plexiform appearance, fascicles of nevus cells following the dermal appendages and neurovascular bundles. Perineural or endoneural extension is a very common f...

Therapy of melanocytic conjunctival tumors.

BACKGROUND Clinical experience of our single center in dealing with pigmented epibulbar lesions - melanocytic conjunctival tumors is presented. Since 2008 we use the topical treatment with mitomycin C (MMC) as an alternative or adjunctive method for excision in the treatment of melanocytic neoplasia of the conjunctiva. METHODS The retrospective case series of 85 patients with pigmented lesion...

Expression of cyclooxygenase-2 in melanocytic skin lesions by immunohistochemistry

Introduction: cyclooxygenase-2 (COX-2) is involved in pathogenesis of various tumors and possibly malignant skin tumors including malignant melanoma; however, there is not enough information about COX-2 expression in benign melanocytic lesions. In the present study we compared the expression levels of COX-2 in malignant melanoma and benign melanocytic lesions. Method: In this analytical study, ...

Brain Tumors Diagnostic by Tumor Imaging Agents

Diagnostic transvitreal fine-needle aspiration biopsy of small melanocytic choroidal tumors in nevus versus melanoma category.

PURPOSE To report an experience with fine-needle aspiration biopsy of selected small melanocytic choroidal tumors during the interval from April 13, 1983, through January 19, 2001. METHODS Retrospective descriptive case series report of 34 patients with a small melanocytic choroidal tumor (maximal diameter, < or = 10 mm; thickness, > or = 1.5 mm but < or = 3 mm) evaluated diagnostically by tr...